Description

3,6-Dihydro-2H-Pyran-4-Boronic Acid Pinacol Ester is a versatile and highly valuable boronic ester building block used in modern synthetic chemistry. Its primary value lies in enabling the efficient construction of complex molecular architectures through reliable cross-coupling reactions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for drug discovery and development.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds, crucial in synthesizing complex organic molecules and heterocycles.
• Pharmaceutical Intermediate: Used in the research and production of active pharmaceutical ingredients (APIs), particularly those containing dihydropyran or tetrahydropyran motifs.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with improved efficacy.
• Ligand and Catalyst Development: Employed in the synthesis of novel boron-containing ligands for catalytic systems.
• Material Science Research: Used in the development of organic electronic materials, polymers, and liquid crystals.
• Chemical Biology Probes: Facilitates the synthesis of molecules used to study biological processes and protein interactions.

Basic Information

Product Name	3,6-Dihydro-2H-Pyran-4-Boronic Acid Pinacol Ester
CAS No.	287944-16-5
Molecular Formula	C11H19BO3
Molecular Weight	210.08 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyran; 2H-Pyran-4-boronic acid, 3,6-dihydro-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester; 3,6-Dihydro-2H-pyran-4-ylboronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyran; DHP-BPin; 3,6-Dihydro-2H-pyran-4-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 3,6-Dihydro-2H-Pyran-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including NMR, HPLC, and GC analysis, to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥95% (Typical 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.