Description

Gambogic Amide CAS NO 286935-60-2 is a bioactive derivative of gambogic acid, a natural compound isolated from the Garcinia hanburyi tree. This compound is of significant interest in pharmaceutical research due to its potent and selective biological activity profile. It serves as a critical reference standard and a key intermediate for researchers and developers in the fields of oncology, neurology, and medicinal chemistry.

Application

• Pharmaceutical Research & Development: A vital reference standard and active pharmaceutical ingredient (API) intermediate for developing novel therapeutics.
• Oncology Studies: Used in biochemical research to investigate anti-cancer mechanisms, including apoptosis induction and metastasis inhibition.
• Neurological Disorder Research: Employed in preclinical studies targeting neurodegenerative pathways and neuroprotective effects.
• Medicinal Chemistry & Lead Optimization: Serves as a core scaffold for the synthesis and structure-activity relationship (SAR) study of new drug candidates.
• Biochemical Assays & Screening: Utilized as a high-purity compound in target validation and high-throughput screening (HTS) platforms.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in cell biology and pharmacology.

Basic Information

Product Name	Gambogic Amide
CAS No.	286935-60-2
Molecular Formula	C38H44O9
Molecular Weight	668.8 g/mol
Synonyms	Gambogamide; Gambogic acid amide; Morellin amide analog; (E)-3-((1R,5aS,6R,9aS)-6-Hydroxy-5a-methyl-8-methylene-1-((E)-3-methylpenta-2,4-dien-1-yl)-2,9-dioxo-1,2,5a,6,7,9,9a,9b-octahydro-3H-oxireno[2,3-a]phenalen-6-yl)acrylamide; Garcinia hanburyi extract derivative
EINECS	Contact for details

Quality Control

Our Gambogic Amide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting research reproducibility.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, store at 2-8°C. The compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.