Description

4-(2,4-Difluorophenoxy)Aniline is a high-purity, advanced pharmaceutical intermediate characterized by its distinct difluorophenoxy aniline structure. This compound matters for its critical role as a versatile building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and anti-inflammatory pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with enhanced efficacy and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small-molecule drugs, especially kinase inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging the fluorine atoms for improved bioactivity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing specialized aromatic amines used in electronic display technologies.
• Polymer Modification: Employed to introduce aniline and fluorinated aromatic groups into polymer chains, altering thermal and optical properties.
• Dye & Pigment Manufacturing: Acts as a precursor for creating azo dyes and other complex colorants with specific light-fastness and hue characteristics.
• Research & Development: Essential for academic and industrial research in organic chemistry, medicinal chemistry, and material science.

Basic Information

Product Name	4-(2,4-Difluorophenoxy)Aniline
CAS No.	286932-63-6
Molecular Formula	C12H9F2NO
Molecular Weight	221.20 g/mol
Synonyms	4-(2,4-Difluorophenoxy)benzenamine; 2,4-Difluorophenyl 4-aminophenyl ether; 4-Amino-2',4'-difluorodiphenyl ether; 1-Amino-4-(2,4-difluorophenoxy)benzene; Benzenamine, 4-(2,4-difluorophenoxy)-; 4-(2,4-Difluorophenoxy)phenylamine; Aniline, 4-(2,4-difluorophenoxy)-
EINECS	Contact for details

Quality Control

Our 4-(2,4-Difluorophenoxy)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.