Description

2-[(Diethoxyphosphorothioyl)Oxy]-6-(2-Thienyl)-4-(Trifluoromethyl)Nicotinonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure incorporating thienyl and phosphorothioyl moieties. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It serves as a key building block for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new compounds with enhanced biological activity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, especially for central nervous system (CNS) and antiviral therapies.
• Agrochemical Research: Used in the development of next-generation insecticides and herbicides, leveraging its phosphorothioate chemistry.
• Chemical Biology Probe: Serves as a specialized scaffold for designing molecular probes to study enzyme inhibition and receptor binding.
• Material Science: Potential monomer or additive in the synthesis of specialty polymers with specific electronic or photophysical properties.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects and process development.

Basic Information

Item	Details
Product Name	2-[(Diethoxyphosphorothioyl)Oxy]-6-(2-Thienyl)-4-(Trifluoromethyl)Nicotinonitrile
CAS No.	286435-85-6
Molecular Formula	C15H14F3N2O3PS2
Molecular Weight	422.38 g/mol
Synonyms	6-(Thiophen-2-yl)-4-(trifluoromethyl)-2-[(diethoxyphosphorothioyl)oxy]nicotinonitrile; O-(6-Cyano-6-(2-thienyl)-4-(trifluoromethyl)-3-pyridyl) O,O-diethyl phosphorothioate; Nicotinonitrile, 2-[(diethoxyphosphorothioyl)oxy]-6-(2-thienyl)-4-(trifluoromethyl)-; Phosphorothioic acid, O-[6-cyano-6-(2-thienyl)-4-(trifluoromethyl)-3-pyridyl] O,O-diethyl ester
EINECS	Contact for details

Quality Control

Every batch of 2-[(Diethoxyphosphorothioyl)Oxy]-6-(2-Thienyl)-4-(Trifluoromethyl)Nicotinonitrile is manufactured under a strict quality management system. We provide comprehensive analytical documentation to ensure traceability and compliance with your project specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive (hygroscopic); ensure containers are sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.