Description

Guanidine-13C Hydrochloride is a stable isotope-labeled derivative of guanidine hydrochloride, where the central carbon atom is replaced by the carbon-13 (13C) isotope. This labeling is critical for applications requiring precise molecular tracking and quantification, such as mass spectrometry-based proteomics and metabolic studies. It is an essential reagent for researchers and manufacturers in pharmaceutical development, analytical chemistry, and life sciences who require high-purity, isotopically enriched compounds for internal standards and tracer studies.

Application

• Internal standard for the quantitative analysis of guanidine and related compounds via Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS).
• Tracer compound in metabolic pathway studies and drug metabolism research (DMPK) to investigate biochemical mechanisms.
• Critical reagent in the synthesis of isotope-labeled peptides, proteins, and nucleic acids for advanced proteomic and genomic research.
• Used in nuclear magnetic resonance (NMR) spectroscopy as a tool for structural elucidation and dynamics studies of biomolecules.
• Component in the preparation of specialized media and buffers for cell culture and protein purification processes in biopharmaceutical manufacturing.
• Standard material for calibrating analytical instruments and validating methods in quality control laboratories.

Basic Information

Product Name	Guanidine-13C Hydrochloride
CAS No.	286013-04-5
Molecular Formula	CH613ClN3
Molecular Weight	96.53 g/mol
Synonyms	Guanidine-13C Hydrochloride; 13C-Guanidine Hydrochloride; Carbamidine-13C Hydrochloride; Aminoformamidine-13C Hydrochloride; Guanidinium-13C Chloride; Iminourea-13C Hydrochloride; Isotope Labeled Guanidine HCl; [13C]Guanidine Hydrochloride
EINECS	Contact for details

Quality Control

Our Guanidine-13C Hydrochloride is manufactured under strict quality systems to ensure batch-to-batch consistency and high isotopic enrichment. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as chemical purity, isotopic purity (13C atom %), and impurity profile. We adhere to relevant industry standards for fine chemicals and can provide material suitable for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Purity (13C atom %)	≥ 99%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.