Description

n-Hydroxy-2-(3-Trifluoromethyl-Pyrazol-1-Yl)-Acetamidine is a specialized heterocyclic organic compound featuring a pyrazole core functionalized with a trifluoromethyl group and an acetamidine moiety. This structure is of significant interest for its role as a key synthetic intermediate in the development of advanced active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate its unique trifluoromethylated pyrazole scaffold into novel molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition or receptor modulation.
• Agrochemical Research: Serves as a precursor for developing new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazole and trifluoromethyl groups.
• Chemical Synthesis: Used in organic synthesis to construct complex heterocyclic systems for material science and specialty chemical applications.
• Biochemical Tool Compound: Potential use in biochemical assays and as a probe for studying biological pathways in academic and industrial research settings.

Basic Information

Product Name	n-Hydroxy-2-(3-Trifluoromethyl-Pyrazol-1-Yl)-Acetamidine
CAS No.	283166-81-4
Molecular Formula	C7H7F3N4O
Molecular Weight	220.16 g/mol
Synonyms	N-Hydroxy-2-(3-(trifluoromethyl)-1H-pyrazol-1-yl)ethanimidamide; 2-(3-Trifluoromethyl-1H-pyrazol-1-yl)-N-hydroxyacetamidine; 1H-Pyrazole-1-acetamidine, N-hydroxy-3-(trifluoromethyl)-; Acetamidine, N-hydroxy-2-[3-(trifluoromethyl)-1H-pyrazol-1-yl]-
EINECS	Contact for details

Quality Control

Our n-Hydroxy-2-(3-Trifluoromethyl-Pyrazol-1-Yl)-Acetamidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.