Description

4,5-Pyridazinediol,1,4,5,6-Tetrahydro-6-(Hydroxymethyl)-,(4R,5R,6R)-(9Ci) is a high-purity, stereochemically defined heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of novel pharmaceutical agents and fine chemicals, offering precise structural control. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in nucleoside analog and antiviral drug discovery.
• Agrochemical Synthesis: Used in the synthesis of novel, high-efficacy crop protection agents and herbicides, leveraging its unique heterocyclic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and advanced materials requiring specific stereochemistry.
• Academic and Industrial Research: A valuable tool for methodological studies in organic chemistry and for exploring new chemical spaces in medicinal chemistry programs.

Basic Information

Product Name	4,5-Pyridazinediol,1,4,5,6-Tetrahydro-6-(Hydroxymethyl)-,(4R,5R,6R)-(9Ci)
CAS No.	280772-06-7
Molecular Formula	C5H10N2O3
Molecular Weight	146.15 g/mol
Synonyms	(4R,5R,6R)-1,4,5,6-Tetrahydro-6-(hydroxymethyl)-4,5-pyridazinediol; (4R,5R,6R)-6-(Hydroxymethyl)-1,4,5,6-tetrahydro-4,5-pyridazinediol; 1,4,5,6-Tetrahydro-6-(hydroxymethyl)-4,5-pyridazinediol, (4R,5R,6R)-; (4R,5R,6R)-6-(Hydroxymethyl)-1,4,5,6-tetrahydropyridazine-4,5-diol; Chiral Tetrahydro Pyridazinediol Derivative
EINECS	Contact for details

Quality Control

Our 4,5-Pyridazinediol,1,4,5,6-Tetrahydro-6-(Hydroxymethyl)-,(4R,5R,6R)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting R&D and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.