Description

4-Fluoro-2-(Trifluoromethyl)Cinnamic Acid is a high-value fluorinated cinnamic acid derivative, distinguished by its unique trifluoromethyl and fluorine substituents. This compound is prized for its role as a versatile synthetic intermediate, enabling the introduction of lipophilic and electron-withdrawing groups into complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating fluorinated organic semiconductors and liquid crystal compounds for advanced display technologies.
• Chemical Research & Development: Employed in academic and industrial labs for studying structure-activity relationships (SAR) and developing novel fluorination methodologies.
• Advanced Polymer Modification: Acts as a monomer or modifier to introduce fluorine-containing side chains into polymers, enhancing their chemical resistance and surface properties.

Basic Information

Product Name	4-Fluoro-2-(Trifluoromethyl)Cinnamic Acid
CAS No.	280753-26-6
Molecular Formula	C₁₀H₆F₄O₂
Molecular Weight	234.15 g/mol
Synonyms	(E)-3-[4-Fluoro-2-(trifluoromethyl)phenyl]acrylic Acid; 4-Fluoro-2-(trifluoromethyl)cinnamate; 2-Trifluoromethyl-4-fluorocinnamic Acid; (E)-4-Fluoro-α-(trifluoromethyl)cinnamic Acid; 280753-26-6; 4-Fluoro-2-trifluoromethylcinnamic Acid; trans-4-Fluoro-2-(trifluoromethyl)cinnamic Acid
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-2-(Trifluoromethyl)Cinnamic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and IR is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.