Description

1-(Trifluoromethyl)Cyclopentane-1-Carboxylic Acid is a specialized fluorinated carboxylic acid building block of significant interest in advanced organic synthesis. Its unique structure, featuring a cyclopentane ring substituted with both a trifluoromethyl group and a carboxylic acid, makes it a valuable precursor for introducing lipophilic and electron-withdrawing motifs. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting metabolic diseases and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated to modify the properties of specialty polymers, imparting increased chemical resistance, thermal stability, or altered surface characteristics.
• Catalyst & Ligand Development: Utilized in the synthesis of novel chiral ligands and organocatalysts for asymmetric synthesis applications.
• Advanced Material Research: Employed in academic and industrial R&D for creating novel fluorinated compounds with tailored physical and chemical properties.

Basic Information

Product Name	1-(Trifluoromethyl)Cyclopentane-1-Carboxylic Acid
CAS No.	277756-44-2
Molecular Formula	C7H9F3O2
Molecular Weight	182.14 g/mol
Synonyms	1-(Trifluoromethyl)cyclopentanecarboxylic acid; Cyclopentanecarboxylic acid, 1-(trifluoromethyl)-; α-(Trifluoromethyl)cyclopentanecarboxylic acid; 1-Carboxy-1-(trifluoromethyl)cyclopentane; Trifluoromethylcyclopentanecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1-(Trifluoromethyl)Cyclopentane-1-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its acidic nature, ensure containers are made of compatible materials such as glass or fluorinated polymers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.