Description

(2R,3R,5S)-3,5-Dimethyl-1-Benzyloxy-2-Hydroxy-8-(4-Methoxyphenoxy)-4-Octanone is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its complex structure, featuring multiple stereocenters and functional groups, makes it a critical intermediate for the development of novel, biologically active molecules. This compound is primarily needed by pharmaceutical R&D and fine chemical synthesis teams focused on creating new therapeutic agents and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new Active Pharmaceutical Ingredients (APIs), particularly for complex target molecules.
• Asymmetric Synthesis: Utilized in stereoselective reactions to construct complex molecular architectures with high enantiomeric purity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Natural Product Synthesis: Acts as a building block for the total synthesis of complex natural products with potential biological activity.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant scale for potential commercial production.
• Reference Standard: Provides a high-purity standard for analytical method development and quality control in related synthetic pathways.

Basic Information

Product Name	(2R,3R,5S)-3,5-Dimethyl-1-Benzyloxy-2-Hydroxy-8-(4-Methoxyphenoxy)-4-Octanone
CAS No.	276690-15-4
Molecular Formula	C24H32O5
Molecular Weight	400.51 g/mol
Synonyms	1-(Benzyloxy)-3,5-dimethyl-2-hydroxy-8-(4-methoxyphenoxy)octan-4-one; (2R,3R,5S)-3,5-Dimethyl-1-(phenylmethoxy)-2-hydroxy-8-[4-(methoxy)phenoxy]-4-octanone; 4-Octanone, 1-(benzyloxy)-3,5-dimethyl-2-hydroxy-8-(4-methoxyphenoxy)-, (2R,3R,5S)-; Benzyl (2R,3R,5S)-2-hydroxy-3,5-dimethyl-8-(4-methoxyphenoxy)-4-oxooctyl ether; Chiral C24 ketone building block
EINECS	Contact for details

Quality Control

Our (2R,3R,5S)-3,5-Dimethyl-1-Benzyloxy-2-Hydroxy-8-(4-Methoxyphenoxy)-4-Octanone is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and development applications. All products undergo rigorous analytical testing, including chiral purity verification. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.