Description

(1R,2S)-1-((2-Hydroxy-3,5-Di-tert-Butyl (CAS No. 275374-67-9) is a high-purity, stereochemically defined chiral compound that serves as a critical building block and intermediate in advanced organic synthesis. Its value lies in its precise molecular architecture, which is essential for imparting specific stereochemical and functional properties to target molecules. This compound is primarily needed by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing novel active ingredients, chiral catalysts, and complex specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in areas requiring high stereoselectivity.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides where specific stereochemistry is crucial for bioactivity.
• Catalyst Ligand Precursor: Serves as a foundational structure for synthesizing sophisticated chiral ligands used in asymmetric catalysis.
• Fine Chemical Manufacturing: Employed in the multistep synthesis of complex, high-value specialty chemicals for electronics and material science.
• Academic & Industrial Research: A valuable reference standard and starting material for methodological development in synthetic organic chemistry.

Basic Information

Product Name	(1R,2S)-1-((2-Hydroxy-3,5-Di-tert-Butyl
CAS No.	275374-67-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(1R,2S)-1-(2-Hydroxy-3,5-di-tert-butylphenyl)ethan-1-ol; 1-(2-Hydroxy-3,5-di-tert-butylphenyl)ethanol (1R,2S)-isomer; 275374-67-9; Chiral hindered phenol derivative; (1R,2S)-HDBE; Chiral di-tert-butylphenol intermediate
EINECS	Contact for details

Quality Control

Our (1R,2S)-1-((2-Hydroxy-3,5-Di-tert-Butyl is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including chiral purity analysis (HPLC/Chiral GC), identity confirmation (IR, NMR), and assay determination. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.