Description

2-Amino-4-benzyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile is a versatile and highly functionalized chromene derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its complex molecular scaffold, which is designed for the efficient construction of pharmacologically active compounds. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is utilized to synthesize novel heterocyclic libraries and active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its chromene core to create compounds with specific biological activity.
• Chemical Biology Probe Synthesis: Employed to create specialized molecular tools for studying enzyme function and biological pathways within academic and industrial research settings.
• Material Science Precursor: Acts as a starting material for the synthesis of organic ligands and complex molecules used in advanced materials and catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-scale API (Active Pharmaceutical Ingredient) development.

Basic Information

Product Name	2-Amino-4-benzyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
CAS No.	275360-59-3
Molecular Formula	C17H16N2O2
Molecular Weight	280.33 g/mol
Synonyms	2-Amino-4-benzyl-5-oxo-4,5,6,7,8,9-hexahydro-4H-chromene-3-carbonitrile; 4H-Chromene-3-carbonitrile, 2-amino-4-benzyl-5,6,7,8-tetrahydro-5-oxo-; 2-Amino-4-benzyl-5-oxo-4,5,6,7,8,9-hexahydrochromene-3-carbonitrile; 275360-59-3; Chromene-3-carbonitrile, 2-amino-4-benzyl-5,6,7,8-tetrahydro-5-oxo-4H-; 2-Amino-4-benzyl-5-oxo-5,6,7,8-tetrahydro-4H-1-benzopyran-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-4-benzyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.