Description

2-Amino-4-(Cyclohex-3-En-1-Yl)-7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 275360-55-9. This compound is a key synthetic building block valued for its complex chromene core structure, which is integral to the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of new chemical entities for therapeutic applications.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Organic Synthesis Research: Serves as a versatile scaffold in academic and industrial R&D for exploring new heterocyclic compounds and reaction methodologies.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies to optimize the biological activity and pharmacokinetic profiles of lead molecules.
• Fine Chemical Production: Employed in the controlled synthesis of specialty chemicals requiring a precise chromene-based molecular architecture.

Basic Information

Product Name	2-Amino-4-(Cyclohex-3-En-1-Yl)-7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile
CAS No.	275360-55-9
Molecular Formula	C18H22N2O2
Molecular Weight	298.38 g/mol
Synonyms	2-Amino-4-(cyclohex-3-en-1-yl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile; 4H-Chromene-3-carbonitrile, 2-amino-4-(3-cyclohexen-1-yl)-5,6,7,8-tetrahydro-7,7-dimethyl-5-oxo-; 2-Amino-4-(cyclohex-3-enyl)-7,7-dimethyl-5-oxo-4,5,6,7,8,8a-hexahydrochromene-3-carbonitrile; Chromene-3-carbonitrile derivative (CAS 275360-55-9); Tetrahydrochromene carbonitrile intermediate.
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(Cyclohex-3-En-1-Yl)-7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound should be kept under an inert atmosphere if long-term stability is required.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.