Description

2H-Pyran-2-One,Tetrahydro-4-Hydroxy-3-Methyl-6-(1-Methylethyl)-,(3R,4R,6S)-(9Ci) is a high-purity, stereochemically defined lactone compound with significant utility in advanced organic synthesis. This product matters as a versatile chiral building block, enabling the construction of complex molecular architectures with precise stereochemical control. It is primarily needed by research and development laboratories, pharmaceutical intermediates manufacturers, and fine chemical producers focused on creating novel active ingredients and fragrances.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a starting material or auxiliary in catalytic asymmetric reactions to introduce specific stereocenters.
• Natural Product Synthesis: A valuable precursor for the laboratory synthesis of natural products containing substituted lactone or tetrahydropyran motifs.
• Flavor & Fragrance Industry: Acts as an intermediate for the production of sophisticated aroma chemicals and flavoring agents.
• Agrochemical Research: Employed in the development of new, stereospecific agrochemicals and plant protection agents.
• Material Science: Investigated as a monomer or precursor for specialized polymers with unique properties.

Basic Information

Item	Detail
Product Name	2H-Pyran-2-One,Tetrahydro-4-Hydroxy-3-Methyl-6-(1-Methylethyl)-,(3R,4R,6S)-(9Ci)
CAS No.	274905-39-4
Molecular Formula	C9H16O3
Molecular Weight	172.22 g/mol
Synonyms	(3R,4R,6S)-Tetrahydro-4-hydroxy-3-methyl-6-(1-methylethyl)-2H-pyran-2-one; (3R,4R,6S)-4-Hydroxy-3-methyl-6-(propan-2-yl)tetrahydro-2H-pyran-2-one; (3R,4R,6S)-Dihydro-4-hydroxy-3-methyl-6-(1-methylethyl)-2(3H)-furanone (tautomeric form); Optically active lactone derivative; Chiral γ-lactone; Stereoisomer of mint lactone.
EINECS	Contact for details

Quality Control

Every batch of our (3R,4R,6S)-Tetrahydro-4-hydroxy-3-methyl-6-(1-methylethyl)-2H-pyran-2-one undergoes rigorous analytical testing to ensure identity, purity, and stereochemical integrity. Our quality commitment includes comprehensive analysis via HPLC, GC, chiral chromatography, and NMR to confirm the specified enantiomeric excess (ee) and chemical purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.