Description

2H-Pyran-2-One,Tetrahydro-4-Hydroxy-3-Methyl-6-(1-Methylethyl)-,(3S,4S,6S)-(9Ci) is a high-purity, stereochemically defined lactone derivative that serves as a critical chiral building block in advanced organic synthesis. Its precise stereochemistry and functional groups make it a valuable intermediate for creating complex molecules with specific biological activities. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high stereochemical purity.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to construct complex natural products and bioactive compounds.
• Flavor & Fragrance Precursor: Serves as a starting material for the synthesis of sophisticated lactone-based aroma chemicals used in premium fragrance and flavor formulations.
• Agrochemical Research: Employed in the development of novel, high-efficacy crop protection agents with specific modes of action.
• Material Science: Investigated as a monomer or modifier for creating specialized polymers with unique properties.
• Academic & Contract Research: Used in university and CRO laboratories for methodological development and exploratory chemistry projects.

Basic Information

Product Name	2H-Pyran-2-One,Tetrahydro-4-Hydroxy-3-Methyl-6-(1-Methylethyl)-,(3S,4S,6S)-(9Ci)
CAS No.	274905-38-3
Molecular Formula	C9H16O3
Molecular Weight	172.22 g/mol
Synonyms	(3S,4S,6S)-Tetrahydro-4-hydroxy-3-methyl-6-(1-methylethyl)-2H-pyran-2-one; (3S,4S,6S)-4-Hydroxy-3-methyl-6-(propan-2-yl)tetrahydro-2H-pyran-2-one; (3S,4S,6S)-4-Hydroxy-3-methyl-6-isopropyltetrahydro-2H-pyran-2-one; A stereoisomer of Whisky Lactone; 4-Hydroxy-3-methyl-6-(1-methylethyl)tetrahydro-2H-pyran-2-one (specified stereochemistry); (3S,4S,6S)-6-Isopropyl-3-methyl-4-hydroxytetrahydro-2H-pyran-2-one; Chiral Lactone Intermediate 274905-38-3
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high stereochemical purity. Quality is verified through advanced analytical techniques including chiral HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with each shipment. We support compliance requirements for cGMP and ISO 9001 standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.