Description

2-o-Methyl-3,5-o-(1-Methylethylidene)-α-D-Glucoheptonic γ-Lactone is a specialized, high-purity chemical intermediate characterized by its unique bicyclic acetal-protected sugar lactone structure. This compound is valued for its role as a key chiral building block in sophisticated organic synthesis, offering precise stereochemical control. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex nucleoside analogs, antiviral agents, and other chiral active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Serves as a chiral auxiliary or starting material for constructing stereodefined carbon frameworks in medicinal chemistry.
• Glycochemistry Research: Used in the development of novel carbohydrate-based drugs, glycomimetics, and prodrugs due to its protected sugar lactone core.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, including flavors, fragrances, and advanced materials requiring specific chirality.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in organic and bioorganic chemistry laboratories.

Basic Information

Product Name	2-o-Methyl-3,5-o-(1-Methylethylidene)-α-D-Glucoheptonic γ-Lactone
CAS No.	270902-65-3
Molecular Formula	C11H18O7
Molecular Weight	262.26 g/mol
Synonyms	2-O-Methyl-3,5-O-(1-methylethylidene)-α-D-glucoheptono-1,4-lactone; 2-O-Methyl-3,5-O-isopropylidene-α-D-glucoheptono-1,4-lactone; α-D-Glucoheptonic acid, 2-O-methyl-3,5-O-(1-methylethylidene)-, γ-lactone; Isopropylidene-protected methyl glucoheptonolactone; Bicyclic sugar lactone derivative
EINECS	Contact for details

Quality Control

We supply this advanced intermediate under a strict quality management system. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical development. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing specifications such as assay (by HPLC), chiral purity, and impurity profiles. Our quality commitment supports compliance with cGMP and ISO guidelines for research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.