Description

Potassium (3,4,5-Trifluorophenyl)Trifluoroborate is a high-purity organotrifluoroborate salt, a crucial building block in modern synthetic chemistry. Its primary value lies in its exceptional stability and reactivity as a coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient synthesis of complex fluorinated aromatic compounds. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, where the introduction of fluorine atoms is a key strategy to modulate biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs) and drug candidates, particularly for oncology, CNS, and antiviral therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where fluorinated aromatic rings enhance efficacy and environmental persistence.
• Material Science Research: Serves as a building block for creating fluorinated organic electronic materials, liquid crystals, and advanced polymers with unique properties.
• Suzuki-Miyaura Cross-Coupling: Functions as a stable, air- and moisture-tolerant boronic acid equivalent for palladium-catalyzed C-C bond formation with aryl/heteroaryl halides.
• Chemical Library Development: Enables the rapid, parallel synthesis of diverse fluorinated compound libraries for high-throughput screening in drug discovery.
• Fluorine Chemistry Research: An important reagent for academic and industrial research focused on incorporating fluorine into complex molecular architectures.

Basic Information

Product Name	Potassium (3,4,5-Trifluorophenyl)Trifluoroborate
CAS No.	267006-28-0
Molecular Formula	C6H2BF6K
Molecular Weight	233.98 g/mol
Synonyms	Potassium (3,4,5-Trifluorophenyl)trifluoroboranuide; (3,4,5-Trifluorophenyl)trifluoroborate Potassium Salt; Potassium Trifluoro(3,4,5-trifluorophenyl)borate; 3,4,5-Trifluorophenyltrifluoroborate Potassium; Potassium 3,4,5-Trifluorophenyltrifluoroborate; K-3,4,5-Trifluorophenyl-BF3; (3,4,5-Trifluorophenyl)BF3K
EINECS	Contact for details

Quality Control

Our production of Potassium (3,4,5-Trifluorophenyl)Trifluoroborate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including NMR (¹H, ¹³C, ¹⁹F, ¹¹B) for structural confirmation and HPLC for purity assessment. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) to prevent decomposition. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
¹H NMR Assay	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.