Description

5-(Tributylstannyl)-2-(Trimethylsilyl)Thiazole CAS NO 263868-71-9 is a highly functionalized organometallic building block that combines both stannyl and silyl protecting groups on a thiazole heterocycle. This compound is valued for its dual reactivity, enabling sequential and selective cross-coupling reactions in complex molecule synthesis. It is primarily sought by researchers and process chemists in the pharmaceutical and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those containing thiazole cores, via Stille cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel active ingredients for crop protection, leveraging its selective reactivity to introduce thiazole motifs.
• Materials Science Research: Employed in the creation of organic semiconductors, ligands for catalysis, and other functional materials where precise molecular control is required.
• Chemical Biology Probes: Serves as a versatile scaffold for labeling and modifying biomolecules in probe and tool compound development.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic synthesis and organometallic chemistry.

Basic Information

Product Name	5-(Tributylstannyl)-2-(Trimethylsilyl)Thiazole
CAS No.	263868-71-9
Molecular Formula	C18H37NSSiSn
Molecular Weight	470.94 g/mol
Synonyms	2-(Trimethylsilyl)-5-(tributylstannyl)thiazole; 5-Tributylstannyl-2-trimethylsilylthiazole; Thiazole, 5-(tributylstannyl)-2-(trimethylsilyl)-; 5-(Tributylstannyl)-2-(trimethylsilyl)-1,3-thiazole
EINECS	Contact for details

Quality Control

Our 5-(Tributylstannyl)-2-(Trimethylsilyl)Thiazole is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by NMR and HPLC), identity confirmation, and residual solvent levels. Our quality system is designed to meet the stringent requirements of advanced synthetic chemistry.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry place, ideally at 2-8°C for long-term stability. This compound is sensitive to moisture and strong bases. Keep away from heat and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Purity (NMR)	≥ 97%
Tin (Sn) Content	~25.2% (Theoretical)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.