Description

4-(Adamantan-1-Yl)Phenyl Trifluoromethanesulfonate is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. This compound matters for its role as a key precursor in the development of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and antiviral applications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as an excellent arylating agent due to the reactive triflate leaving group.
• Material Science Research: Used in the development of organic semiconductors and advanced polymers where the adamantyl group imparts thermal stability.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for catalysis and molecular recognition.
• Agrochemical Synthesis: Acts as a precursor for developing new crop protection agents with enhanced efficacy.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	4-(Adamantan-1-Yl)Phenyl Trifluoromethanesulfonate
CAS No.	263398-16-9
Molecular Formula	C₁₇H₁₉F₃O₃S
Molecular Weight	360.39 g/mol
Synonyms	4-(1-Adamantyl)phenyl trifluoromethanesulfonate; 4-Adamantylphenyl Triflate; 1-[4-(Trifluoromethanesulfonyloxy)phenyl]adamantane; p-Adamantylphenyl Triflate; Trifluoromethanesulfonic Acid 4-(1-Adamantyl)phenyl Ester; 4-(Adamantan-1-yl)phenyl Triflate; ADPT; 4-(Tricyclo[3.3.1.1³,⁷]dec-1-yl)phenyl trifluoromethanesulfonate
EINECS	Contact for details

Quality Control

Our 4-(Adamantan-1-Yl)Phenyl Trifluoromethanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are provided with every shipment to guarantee consistent quality and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.