Description

3-Chloro-2,6-Difluorobenzylamine is a high-purity, multi-functional aromatic amine building block of significant commercial importance. Its unique structure, featuring both chloro and fluoro substituents, makes it a critical intermediate for synthesizing advanced pharmaceutical compounds and agrochemicals. This compound is essential for R&D and production chemists in the life sciences and specialty chemical industries seeking to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the difluoro and chloro groups contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of monomers and functional polymers for advanced materials with specific electronic or surface properties.
• Organic Synthesis Building Block: Utilized in various coupling reactions (e.g., Buchwald-Hartwig amination) and as a versatile amine component for constructing complex molecular architectures.

Basic Information

Product Name	3-Chloro-2,6-Difluorobenzylamine
CAS No.	261762-46-3
Molecular Formula	C7H6ClF2N
Molecular Weight	177.58 g/mol
Synonyms	(3-Chloro-2,6-difluorophenyl)methanamine; 2,6-Difluoro-3-chlorobenzylamine; 1-(3-Chloro-2,6-difluorophenyl)methanamine; Benzenemethanamine, 3-chloro-2,6-difluoro-; 3-Chloro-2,6-difluorobenzyl amine; α-Amino-3-chloro-2,6-difluorotoluene
EINECS	Contact for details

Quality Control

Our 3-Chloro-2,6-Difluorobenzylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical and advanced agrochemical R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.