Description

2-Bromo-4-(Bromomethyl)-1-Methylbenzene is a versatile brominated aromatic building block of significant interest in advanced organic synthesis. Its value lies in its dual reactive sites, which allow for selective functionalization and the construction of complex molecular architectures. This compound is primarily needed by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting specific receptors or enzymes.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the bromine atoms serve as handles for further chemical modification.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials requiring specific brominated aromatic cores.
• Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form biaryl and other conjugated systems.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	2-Bromo-4-(Bromomethyl)-1-Methylbenzene
CAS No.	259231-26-0
Molecular Formula	C8H8Br2
Molecular Weight	263.96 g/mol
Synonyms	1-Methyl-2-bromo-4-(bromomethyl)benzene; 4-Bromomethyl-2-bromotoluene; 2-Bromo-4-bromomethyltoluene; 2,4-Dibromomethyltoluene; alpha,2-Dibromo-p-xylene; Toluene, 2-bromo-4-(bromomethyl)-; 2-Bromo-α-bromo-p-xylene; p-Xylene, alpha,2-dibromo-
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-(Bromomethyl)-1-Methylbenzene is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.