Description

Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, 6-Hydroxy- (9Ci) is a high-purity, functionalized norbornane derivative that serves as a versatile chiral building block and synthetic intermediate. Its rigid bicyclic framework and strategically positioned hydroxyl and carboxylic acid functional groups make it invaluable for constructing complex molecular architectures with precise stereochemistry. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for applications in asymmetric synthesis, ligand design, and the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon for the asymmetric synthesis of complex drug candidates, particularly in neurology and oncology research.
• Ligand and Catalyst Precursor: Used to develop novel chiral ligands for asymmetric catalysis and organometallic complexes.
• Advanced Material Monomer: Serves as a building block for high-performance polymers, resins, and liquid crystals due to its rigid norbornane core.
• Agrochemical Research: Employed in the synthesis of novel, stereochemically defined bioactive compounds for crop protection.
• Academic & R&D: A valuable tool in methodological organic chemistry research for studying cycloaddition reactions and stereoselective transformations.
• Flavor & Fragrance Chemistry: Potential intermediate for creating unique, structurally constrained aroma molecules.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, 6-Hydroxy- (9Ci)
CAS No.	258345-33-4
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	6-Hydroxybicyclo[2.2.1]heptane-2-carboxylic acid; 6-Hydroxynorbornane-2-carboxylic acid; endo-6-Hydroxybicyclo[2.2.1]heptane-2-carboxylic acid; 2-Norbornanecarboxylic acid, 6-hydroxy-; (1R,2S,4R,6S)-6-Hydroxybicyclo[2.2.1]heptane-2-carboxylic acid (for specific enantiomer); Hydroxylated Norbornane Carboxylic Acid
EINECS	Contact for details

Quality Control

We supply Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, 6-Hydroxy- (9Ci) in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (if applicable), and impurity profiles is provided with each shipment. We adhere to cGMP principles for manufacturing where required, ensuring traceability and documentation for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). For long-term storage, consider storing under an inert atmosphere to prevent potential oxidation. Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (if applicable)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.