Description

Carbamic Acid, [3-[(Aminocarbonyl)Amino]Propyl]-, 1,1-Dimethylethyl Ester (9Ci) is a specialized carbamate derivative featuring both a tert-butyl ester and a ureido functional group, making it a valuable protected intermediate in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular scaffolds for constructing complex molecules, particularly in pharmaceutical development. Its primary utility lies in serving as a key building block for the synthesis of active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where controlled reactivity and high purity are paramount.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its carbamate structure contributes to biological activity.
• Peptide Mimetics & PROTACs: Serves as a versatile linker or spacer unit in the design of peptide-like molecules and Proteolysis Targeting Chimeras (PROTACs) for targeted protein degradation.
• Polymer Science: Acts as a functional monomer or cross-linking agent for creating specialty polymers with specific ureido-based properties.
• Chemical Biology Research: Employed as a tool compound or probe in biochemical studies to investigate enzyme inhibition or cellular signaling pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	Carbamic Acid, [3-[(Aminocarbonyl)Amino]Propyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	258332-61-5
Molecular Formula	C9H19N3O3
Molecular Weight	217.27 g/mol
Synonyms	tert-Butyl N-[3-(aminocarbonylamino)propyl]carbamate; 1,1-Dimethylethyl N-[3-[(aminocarbonyl)amino]propyl]carbamate; N-(3-Aminopropyl)-N'-Boc-urea; Boc-APU; 3-[(tert-Butoxycarbonyl)amino]propylurea; N-Boc-1,3-diaminopropane urea derivative; Ureido derivative of Boc-1,3-diaminopropane
EINECS	Contact for details

Quality Control

Every batch of Carbamic Acid, [3-[(Aminocarbonyl)Amino]Propyl]-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent lot-to-lot quality suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent decomposition. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.