Description

2-Hydroxybicyclo[3.2.1]Octane-6-Carboxylic Acid is a specialized bicyclic organic compound featuring both carboxylic acid and hydroxyl functional groups on a rigid carbon framework. This unique structure makes it a valuable chiral building block and intermediate in advanced organic synthesis. It is primarily sought after by research and development chemists in the pharmaceutical and fine chemical industries for the construction of complex molecules, including potential active pharmaceutical ingredients (APIs) and novel materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic compounds, particularly for central nervous system (CNS) agents or complex natural product analogs.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in catalytic asymmetric reactions to introduce stereochemical complexity into target molecules.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value specialty chemicals, fragrances, and advanced polymers.
• Academic & Industrial Research: Used in methodological studies and as a model compound for investigating new synthetic routes and reaction mechanisms involving strained bicyclic systems.
• Ligand and Catalyst Development: The functional groups can be modified to create novel chelating ligands or organocatalysts for use in transition metal catalysis or organocatalysis.

Basic Information

Product Name	2-Hydroxybicyclo[3.2.1]Octane-6-Carboxylic Acid
CAS No.	257932-29-9
Molecular Formula	C9H14O3
Molecular Weight	170.21 g/mol
Synonyms	6-Carboxy-2-hydroxybicyclo[3.2.1]octane; Bicyclo[3.2.1]octane-6-carboxylic acid, 2-hydroxy-; 2-Hydroxybicyclo[3.2.1]octane-6-carboxylic acid; (1R,2S,5R,6S)-6-Carboxy-2-hydroxybicyclo[3.2.1]octane (stereoisomer); (1S,2R,5S,6R)-6-Carboxy-2-hydroxybicyclo[3.2.1]octane (stereoisomer); 2-Hydroxy-6-bicyclo[3.2.1]octanecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Hydroxybicyclo[3.2.1]Octane-6-Carboxylic Acid is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and relevant physical data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.