Description

2-Azetidinecarboxylic Acid, 1-(Chloroacetyl)-, Methyl Ester (9Ci) is a high-value, heterocyclic building block primarily used in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceuticals and bioactive molecules, particularly those targeting protease inhibition. Pharmaceutical R&D laboratories and fine chemical manufacturers need it to construct complex azetidine-based scaffolds, which are increasingly important in modern medicinal chemistry for creating new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, especially protease inhibitors and other bioactive molecules containing the azetidine ring.
• Medicinal Chemistry Research: Used in R&D for structure-activity relationship (SAR) studies and the exploration of new chemical entities (NCEs) in drug discovery programs.
• Fine Chemical Synthesis: Serves as a specialized precursor for creating complex, high-value heterocyclic compounds in custom synthesis and contract manufacturing.
• Bioconjugation & Probe Development: The reactive chloroacetyl group enables its use in bioconjugation chemistry for creating labeled probes or antibody-drug conjugates (ADCs).
• Agrochemical Research: Potential intermediate in the development of new generation pesticides and herbicides with novel modes of action.
• Academic & Institutional Research: Employed in universities and research institutes for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	2-Azetidinecarboxylic Acid, 1-(Chloroacetyl)-, Methyl Ester (9Ci)
CAS No.	255882-69-0
Molecular Formula	C7H10ClNO3
Molecular Weight	191.61 g/mol
Synonyms	Methyl 1-(Chloroacetyl)azetidine-2-carboxylate; 1-(Chloroacetyl)azetidine-2-carboxylic Acid Methyl Ester; Azetidine-2-carboxylic Acid, 1-(Chloroacetyl)-, Methyl Ester; 1-Chloroacetyl-2-carbomethoxyazetidine; Methyl 1-Chloroacetylazetidine-2-carboxylate; (9CI) Identifier; Azetidine Derivative CAS 255882-69-0
EINECS	Contact for details

Quality Control

Our 2-Azetidinecarboxylic Acid, 1-(Chloroacetyl)-, Methyl Ester (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the exacting standards required for pharmaceutical R&D and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere if possible and opened only in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.