Description

Bis-Peg3-Sulfonic Acid CAS NO 255831-16-4 is a high-purity, functionalized polyethylene glycol derivative featuring terminal sulfonic acid groups, making it a valuable hydrophilic linker and building block. This compound is critical for introducing solubility, polarity, and ionic character into complex molecules and materials. It is primarily sought by researchers and manufacturers in the pharmaceutical, bioconjugation, and advanced materials sectors for applications requiring precise chemical modification and enhanced aqueous compatibility.

Application

• Bioconjugation & Protein Modification: Used as a hydrophilic, charged linker for attaching drugs, dyes, or other functional groups to proteins, antibodies, or peptides to improve solubility and pharmacokinetics.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for synthesizing hydrogels, ion-exchange resins, and functional polymers with tailored surface properties.
• Pharmaceutical Intermediates: Acts as a key synthetic intermediate in the development of prodrugs and novel active pharmaceutical ingredients (APIs) requiring sulfonate functionality.
• Surface Functionalization: Employed to modify nanoparticles, quantum dots, or diagnostic assay surfaces to enhance stability in biological media and reduce non-specific binding.
• Catalyst & Ligand Synthesis: Utilized in the preparation of water-soluble catalysts and ligands for green chemistry and aqueous-phase reactions.
• Chromatography & Separation Media: Incorporated into stationary phases for HPLC or other chromatographic techniques to achieve specific separation profiles based on ionic interaction.

Basic Information

Product Name	Bis-Peg3-Sulfonic Acid
CAS No.	255831-16-4
Molecular Formula	C12H26O10S2
Molecular Weight	394.46 g/mol
Synonyms	1,11-Bis(sulfo)-3,6,9-trioxaundecane; 3,6,9-Trioxaundecane-1,11-disulfonic acid; PEG3-disulfonic acid; Bis(PEG3) sulfonic acid; 2,2'-(Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) disulfonate; Disulfonated triethylene glycol; 1,1'-[1,2-Ethanediylbis(oxy-3,1-propanediyl)] ester sulfuric acid
EINECS	Contact for details

Quality Control

Our Bis-Peg3-Sulfonic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and commercial applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere (e.g., nitrogen or argon) to maintain optimal purity and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.