Description

Ethyl 4-Aminotetrahydropyran-4-Carboxylate Hcl is a high-purity pharmaceutical intermediate and versatile organic building block. This compound is valued for its unique tetrahydropyran scaffold, which is a privileged structure in medicinal chemistry for modulating drug-like properties. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates targeting central nervous system (CNS) disorders, infectious diseases, and metabolic conditions.
• Medicinal Chemistry Research: Used in scaffold hopping and structure-activity relationship (SAR) studies to explore new chemical space and improve pharmacokinetic profiles.
• Agrochemical Synthesis: Intermediate in the development of new herbicides, fungicides, and insecticides that require a saturated oxygen heterocycle.
• Chemical Biology Probes: Serves as a precursor for designing molecular probes and tool compounds to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds at various scales.

Basic Information

Product Name	Ethyl 4-Aminotetrahydropyran-4-Carboxylate Hcl
CAS No.	255390-15-9
Molecular Formula	C9H18ClNO3
Molecular Weight	223.70 g/mol
Synonyms	4-Amino-tetrahydropyran-4-carboxylic acid ethyl ester hydrochloride; Ethyl 4-aminooxane-4-carboxylate hydrochloride; 4-(Ethoxycarbonyl)-4-aminotetrahydropyran hydrochloride; 4-Amino-4-carbethoxytetrahydropyran hydrochloride; 4-Aminotetrahydropyran-4-carboxylic Acid Ethyl Ester HCl; 255390-15-9; UNII-9F6H3I8F1P
EINECS	Contact for details

Quality Control

Our Ethyl 4-Aminotetrahydropyran-4-Carboxylate Hcl is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.