Description

2-Furanmethanol, 5-Ethynyltetrahydro-, (2R,5S)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex pharmaceutical molecules and fine chemicals, where its specific stereochemistry and functional groups enable precise molecular construction. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for complex, stereoselective targets.
• Asymmetric Catalysis Research: Used as a ligand precursor or a model substrate in the development of new catalytic asymmetric reactions.
• Agrochemical Synthesis: Employed in the research and development of novel, stereochemically pure crop protection agents.
• Fine Chemical Production: Acts as a building block for the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry and for creating compound libraries for biological screening.

Basic Information

Product Name	2-Furanmethanol, 5-Ethynyltetrahydro-, (2R,5S)- (9Ci)
CAS No.	254891-75-3
Molecular Formula	C7H8O2
Molecular Weight	124.14 g/mol
Synonyms	(2R,5S)-5-Ethynyltetrahydrofurfuryl Alcohol; (2R,5S)-5-Ethynyltetrahydro-2-furanmethanol; (2R,5S)-5-Ethynyloxolane-2-methanol; Tetrahydro-5-ethynyl-2-furanmethanol, (2R,5S)-; Chiral Ethynyl Tetrahydrofurfuryl Alcohol; (2R,5S)-rel-5-Ethynyltetrahydro-2-furancarbinol
EINECS	Contact for details

Quality Control

Our 2-Furanmethanol, 5-Ethynyltetrahydro-, (2R,5S)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications for identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.