Description

2-Chloro-4-Cyanobenzenesulfonyl Chloride is a versatile and highly reactive aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a sulfonyl chloride and a nitrile group, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel sulfonamides and other functionalized aromatic systems.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the sulfonamide moiety can enhance biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Dye and Pigment Manufacturing: Intermediate for creating sulfonated dyes and colorants with improved solubility and fastness properties.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes and molecular tags for proteomics and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global fine chemicals market.

Basic Information

Item	Detail
Product Name	2-Chloro-4-Cyanobenzenesulfonyl Chloride
CAS No.	254749-11-6
Molecular Formula	C7H3Cl2NO2S
Molecular Weight	236.07 g/mol
Synonyms	2-Chloro-4-cyanobenzenesulfonyl chloride; 4-Cyano-2-chlorobenzenesulfonyl chloride; 2-Chloro-4-cyanobenzene-1-sulfonyl chloride; Benzenesulfonyl chloride, 2-chloro-4-cyano-; (2-Chloro-4-cyanophenyl)sulfonyl chloride; 254749-11-6; 2-Chloro-4-cyanophenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-Cyanobenzenesulfonyl Chloride is manufactured and tested under a strict quality management system. We ensure the product meets high-purity standards suitable for research and industrial synthesis. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.