Description

4-(Tributylstannyl)-2-(Trimethylsilyl)Thiazole is a highly functionalized organometallic building block, specifically engineered for advanced cross-coupling reactions. Its core value lies in enabling the precise, high-yield synthesis of complex heterocyclic compounds that are difficult to access via traditional methods. This specialized reagent is essential for R&D chemists and process development teams in the pharmaceutical, agrochemical, and materials science industries, where it facilitates the creation of novel active ingredients and functional materials.

Application

• As a key Stille coupling reagent for the synthesis of complex, substituted thiazole derivatives in pharmaceutical research.
• Building block for the development of organic electronic materials, including OLEDs and organic semiconductors.
• Intermediate in the synthesis of agrochemicals, such as novel fungicides and herbicides with tailored properties.
• Precursor for ligand synthesis in catalysis and coordination chemistry.
• Used in polymer modification to introduce functional thiazole moieties into polymer backbones.
• Research chemical for exploring new C-C bond formation methodologies in academic and industrial laboratories.

Basic Information

Product Name	4-(Tributylstannyl)-2-(Trimethylsilyl)Thiazole
CAS No.	252562-80-4
Molecular Formula	C18H37NSSiSn
Molecular Weight	470.34 g/mol
Synonyms	2-(Trimethylsilyl)-4-(tributylstannyl)thiazole; 4-Tributylstannyl-2-trimethylsilylthiazole; Thiazole, 4-(tributylstannyl)-2-(trimethylsilyl)-; 4-(Tributylstannyl)-2-(trimethylsilyl)-1,3-thiazole; 2-Trimethylsilyl-4-tributylstannylthiazole; 4-(SnBu3)-2-(TMS)-Thiazole; Stannane, tributyl[2-(trimethylsilyl)-4-thiazolyl]-
EINECS	Contact for details

Quality Control

Our production of 4-(Tributylstannyl)-2-(Trimethylsilyl)Thiazole adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is characterized by advanced analytical techniques including NMR (1H, 13C, 119Sn), GC-MS, and HPLC to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry place at 2-8°C. This compound is sensitive to moisture and strong bases; ensure the storage area is well-ventilated and separate from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 95%
Purity (HPLC)	≥ 95%
Tin (Sn) Content	Contact for details
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.