Description

4-Aminotetrahydropyran-4-Carboxylic Acid Ethyl Ester is a versatile and high-purity chemical intermediate of significant importance in advanced organic synthesis. Its unique bicyclic structure, featuring both an amino and an ester functional group, makes it a critical building block for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where its structural motif can contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetics Research: The aminotetrahydropyran scaffold is valuable for designing peptide analogs with improved metabolic stability and bioavailability.
• Academic & Industrial R&D: Employed in medicinal chemistry programs for library synthesis and structure-activity relationship (SAR) studies.

Basic Information

Product Name	4-Aminotetrahydropyran-4-Carboxylic Acid Ethyl Ester
CAS No.	246547-26-2
Molecular Formula	C8H15NO3
Molecular Weight	173.21 g/mol
Synonyms	Ethyl 4-Aminotetrahydropyran-4-carboxylate; 4-Aminooxane-4-carboxylic acid ethyl ester; 4-Amino-THP-4-carboxylic acid ethyl ester; 4-Aminotetrahydro-2H-pyran-4-carboxylic Acid Ethyl Ester; 4-Ethoxycarbonyl-4-aminotetrahydropyran; 4-Amino-4-ethoxycarbonyltetrahydropyran; 4-Carbethoxy-4-aminotetrahydropyran; 4-Aminotetrahydropyran-4-carboxylic acid, ethyl ester
EINECS	Contact for details

Quality Control

Our production of 4-Aminotetrahydropyran-4-Carboxylic Acid Ethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.