Description

1,3-Bis(2,4,6-Trimethylphenyl)-4,5-Dihydroimidazolium Tetrafluoroborate is a highly specialized N-heterocyclic carbene (NHC) precursor salt, valued for its role as a robust and versatile ligand source in organometallic catalysis. Its primary commercial significance lies in enabling highly efficient and selective transition metal-catalyzed reactions, which are critical for advanced chemical synthesis. This compound is essential for R&D and production within the pharmaceutical, agrochemical, and advanced materials sectors, where it facilitates the development of novel compounds and complex molecular architectures.

Application

• Precursor for N-Heterocyclic Carbene (NHC) Ligands: Serves as a stable, air-handleable source for generating highly active NHC ligands used in organometallic catalysis.
• Cross-Coupling Catalysis: Employed in Buchwald-Hartwig amination, Suzuki-Miyaura, and Negishi cross-coupling reactions for C-C and C-N bond formation.
• Olefin Metathesis: Key component in the synthesis of ruthenium-based Grubbs and Hoveyda-Grubbs type catalysts for ring-closing metathesis (RCM) and cross-metathesis.
• Pharmaceutical Intermediate Synthesis: Facilitates the construction of complex, chiral molecules in API (Active Pharmaceutical Ingredient) development.
• Polymerization Catalyst Systems: Used in the development of Ziegler-Natta and single-site catalysts for the production of specialty polymers with controlled architectures.
• Agrochemical Synthesis: Enables efficient synthesis of novel active ingredients requiring precise catalytic transformations.
• Academic and Industrial R&D: A fundamental reagent for exploring new catalytic methodologies and reaction pathways in synthetic chemistry.

Basic Information

Product Name	1,3-Bis(2,4,6-Trimethylphenyl)-4,5-Dihydroimidazolium Tetrafluoroborate
CAS No.	245679-18-9
Molecular Formula	C21H27BF4N2
Molecular Weight	394.26 g/mol
Synonyms	1,3-Bis(2,4,6-Trimethylphenyl)imidazolinium Tetrafluoroborate; 1,3-Bis(mesityl)imidazolinium Tetrafluoroborate; 1,3-Dimesitylimidazolinium Tetrafluoroborate; IMes·HBF4; SIPr·HBF4 (common abbreviation); NHC Precursor Salt; N-Heterocyclic Carbene Salt; 4,5-Dihydro-1,3-bis(2,4,6-trimethylphenyl)-1H-imidazol-3-ium tetrafluoroborate
EINECS	Contact for details

Quality Control

Our 1,3-Bis(2,4,6-Trimethylphenyl)-4,5-Dihydroimidazolium Tetrafluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and consistent performance as a catalyst precursor. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.