Description

n-Carbobenzoxy-2-Nitrobenzenesulfonamide is a specialized chemical building block used in advanced organic synthesis. This compound is valued for its role as a protected intermediate, enabling the controlled construction of complex molecules in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists working on novel active ingredients, particularly where selective amine protection and deprotection strategies are required.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially for protease inhibitors and other small molecule therapeutics.
• Peptide Chemistry: Serves as a protecting group reagent for amines in solid-phase and solution-phase peptide synthesis.
• Agrochemical Research: Used in the development of new pesticides and herbicides as a precursor for active ingredient synthesis.
• Chemical Biology Probes: Employed in the creation of labeled compounds and molecular probes for studying biological mechanisms.
• Custom Synthesis: A critical reagent for contract research and manufacturing organizations (CROs/CMOs) producing bespoke organic molecules.
• Academic Research: Utilized in university laboratories for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	n-Carbobenzoxy-2-Nitrobenzenesulfonamide
CAS No.	245365-64-4
Molecular Formula	C14H12N2O6S
Molecular Weight	336.32 g/mol
Synonyms	2-Nitrobenzenesulfonyl Carbobenzoxy Amide; Cbz-2-Nosyl Amide; N-[(Benzyloxy)carbonyl]-2-nitrobenzenesulfonamide; Z-2-Nosyl-NH2; (Benzyloxy)carbonyl 2-Nitrobenzenesulfonamide; Carbobenzoxy-2-Nitrobenzenesulfonyl Amide; N-Cbz-2-Nitrobenzenesulfonamide; 2-Nosyl-Cbz-NH2
EINECS	Contact for details

Quality Control

Our n-Carbobenzoxy-2-Nitrobenzenesulfonamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and compliance needs in advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.