Description

2,3,4,5,6-Pentafluorophenyl 4-Nitrobenzenesulfonate is a high-purity, specialized sulfonate ester derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its dual functionality, acting as an excellent leaving group and a versatile intermediate for introducing the pentafluorophenyl moiety into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries, where it facilitates the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing complex molecular architectures.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring fluorinated aromatic components.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis.
• Functional Material Development: Employed in the research and production of advanced polymers, liquid crystals, and electronic materials.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Proteomics and Bioconjugation: Potential use in chemical biology for labeling proteins or other biomolecules due to its reactive sulfonate ester group.

Basic Information

Product Name	2,3,4,5,6-Pentafluorophenyl 4-Nitrobenzenesulfonate
CAS No.	244633-31-6
Molecular Formula	C12H4F5NO5S
Molecular Weight	369.22 g/mol
Synonyms	4-Nitrobenzenesulfonic Acid 2,3,4,5,6-Pentafluorophenyl Ester; Pentafluorophenyl 4-Nitrobenzenesulfonate; 4-Nitrobenzenesulfonyl Pentafluorophenyl Ester; PNBS-PFP Ester; 2,3,4,5,6-Pentafluorophenyl 4-Nitrobenzene-1-sulfonate; 4-Nitrobenzenesulfonatooxy-2,3,4,5,6-pentafluorobenzene
EINECS	Contact for details

Quality Control

Our 2,3,4,5,6-Pentafluorophenyl 4-Nitrobenzenesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.