Description

Urea, n-[4-(Trifluoromethoxy)Phenyl]-N'-[4-(Trifluoromethyl)-2-Pyridinyl]- is a specialized organic compound featuring a urea core flanked by fluorinated aromatic and heteroaromatic substituents, making it a valuable intermediate for advanced chemical synthesis. Its molecular architecture, incorporating both trifluoromethoxy and trifluoromethyl groups, is engineered to impart unique electronic and steric properties critical for developing high-performance materials and active pharmaceutical ingredients. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate fluorinated motifs to enhance metabolic stability, lipophilicity, and binding affinity.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors or other small-molecule therapeutics where fluorinated groups are advantageous.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, or insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl and trifluoromethoxy groups.
• Advanced Material Synthesis: Acts as a precursor for creating specialized polymers, liquid crystals, or organic electronic materials that require precise fluorination for optimal performance.
• Chemical Biology Probe Development: Utilized in constructing molecular probes and tags for studying biological processes, where its fluorinated structure can aid in detection (e.g., 19F NMR) or improve membrane permeability.
• Custom Synthesis & Contract Manufacturing: A critical intermediate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving clients in life sciences.

Basic Information

Product Name	Urea, n-[4-(Trifluoromethoxy)Phenyl]-N'-[4-(Trifluoromethyl)-2-Pyridinyl]-
CAS No.	244125-74-4
Molecular Formula	C14H9F6N3O2
Molecular Weight	365.24 g/mol
Synonyms	1-[4-(Trifluoromethoxy)phenyl]-3-[4-(trifluoromethyl)pyridin-2-yl]urea; N-[4-(Trifluoromethoxy)phenyl]-N'-[4-(trifluoromethyl)pyridin-2-yl]urea; 2-({[4-(Trifluoromethoxy)phenyl]carbamoyl}amino)-4-(trifluoromethyl)pyridine; Urea, N-(4-(trifluoromethoxy)phenyl)-N'-(4-(trifluoromethyl)-2-pyridinyl)-; 244125-74-4
EINECS	Contact for details

Quality Control

Every batch of Urea, n-[4-(Trifluoromethoxy)Phenyl]-N'-[4-(Trifluoromethyl)-2-Pyridinyl]- is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, ensuring full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.