Description

2-Amino-5-(Tributylstannyl)-1,3-Thiazole, n-Boc Protected is a high-purity, organotin-functionalized thiazole building block, specifically designed for advanced synthetic chemistry. This compound is critical for facilitating efficient cross-coupling reactions, particularly Stille couplings, enabling the precise construction of complex molecular architectures. It is an essential intermediate for researchers and process chemists in pharmaceutical development, agrochemical research, and materials science, where reliable access to specialized organometallic reagents is paramount.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and complex heterocyclic compounds via Stille cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides that require the incorporation of functionalized thiazole motifs.
• Materials Science Research: Serves as a precursor for creating organic electronic materials, ligands for catalysis, and metal-organic frameworks (MOFs).
• Chemical Biology & Probe Development: Enables the site-specific labeling and modification of biomolecules for diagnostic and research applications.
• Academic & Industrial R&D: A valuable reagent for methodology development in organic synthesis and catalysis studies.
• Custom Synthesis & Contract Manufacturing: Supplied as a high-quality starting material for custom synthesis projects requiring organotin chemistry.

Basic Information

Product Name	2-Amino-5-(Tributylstannyl)-1,3-Thiazole, n-Boc Protected
CAS No.	243972-26-1
Molecular Formula	C20H38N2O2SSn
Molecular Weight	489.27 g/mol
Synonyms	5-(Tributylstannyl)-2-[(tert-butoxycarbonyl)amino]-1,3-thiazole; tert-Butyl N-[5-(tributylstannyl)-1,3-thiazol-2-yl]carbamate; 2-((tert-Butoxycarbonyl)amino)-5-(tributylstannyl)thiazole; Boc-2-Amino-5-(tributylstannyl)thiazole; N-Boc-2-Amino-5-tributylstannylthiazole; Organotin Thiazole Building Block; Stille Coupling Reagent; CAS 243972-26-1
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-5-(Tributylstannyl)-1,3-Thiazole, n-Boc Protected is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical applications. Our products undergo rigorous quality testing, including advanced spectroscopic and chromatographic methods, to ensure compliance with industry standards. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This compound is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from strong alkali/organic solvent. Allow the sealed container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Tin (Sn) Content	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.