Description

(2R,3R)-2-(Phenylselanyl)-3-(Trifluoromethylsulfonyl)Cyclopentanone is a high-purity, chiral organoselenium building block featuring a trifluoromethylsulfonyl (triflyl) group. This compound is a critical intermediate in advanced organic synthesis, valued for its ability to introduce both selenium and a powerful electron-withdrawing group in a stereocontrolled manner. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for constructing complex drug candidates, particularly in medicinal chemistry programs targeting new therapeutic entities.
• Asymmetric Synthesis: Utilized in stereoselective reactions, including Michael additions and nucleophilic substitutions, to create enantiomerically pure compounds.
• Organoselenium Chemistry: Serves as a versatile selenium transfer reagent for introducing phenylselanyl groups into organic frameworks under mild conditions.
• Agrochemical Research: Employed in the development of novel pesticides and herbicides where the unique properties of selenium and fluorine are beneficial.
• Material Science Precursor: Potential use in synthesizing specialized ligands or functional materials with tailored electronic properties.
• Academic & R&D: A valuable tool for methodological development in organic chemistry laboratories exploring new reaction pathways.

Basic Information

Product Name	(2R,3R)-2-(Phenylselanyl)-3-(Trifluoromethylsulfonyl)Cyclopentanone
CAS No.	235746-88-0
Molecular Formula	C12H11F3O3SSe
Molecular Weight	371.23 g/mol
Synonyms	(2R,3R)-2-(Phenylselanyl)-3-[(trifluoromethyl)sulfonyl]cyclopentanone; (2R,3R)-2-(Phenylselanyl)-3-(triflyl)cyclopentanone; 2-(Phenylselanyl)-3-(trifluoromethylsulfonyl)cyclopentanone, (2R,3R)-; (2R,3R)-2-(Benzeneselenyl)-3-(trifluoromethanesulfonyl)cyclopentanone; (2R,3R)-2-(Phenylseleno)-3-(trifluoromethanesulfonyl)cyclopentanone; (2R,3R)-2-(Phenylselanyl)-3-(Tf)Cyclopentanone; CAS 235746-88-0
EINECS	Contact for details

Quality Control

Our (2R,3R)-2-(Phenylselanyl)-3-(Trifluoromethylsulfonyl)Cyclopentanone is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, enantiomeric excess, and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep container tightly sealed under an inert atmosphere such as nitrogen or argon. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.