Description

3-Trifluoromethoxyphenylthiourea is a specialized organic building block featuring a trifluoromethoxy-substituted phenyl ring and a thiourea functional group. This compound is valued for its role as a key intermediate in the synthesis of advanced molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, where its unique structure enables the introduction of specific pharmacophores and modulates physicochemical properties.

Application

• Pharmaceutical Intermediate: A crucial building block for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for functional materials, such as ligands for catalysis or monomers for specialty polymers with tailored properties.
• Chemical Biology Probe Development: Utilized in the design of molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical companies for use in custom synthesis projects and scale-up processes.

Basic Information

Product Name	3-Trifluoromethoxyphenylthiourea
CAS No.	235101-42-5
Molecular Formula	C9H7F3N2OS
Molecular Weight	248.22 g/mol
Synonyms	1-(3-(Trifluoromethoxy)phenyl)thiourea; N-(3-Trifluoromethoxyphenyl)thiourea; 3-(Trifluoromethoxy)phenylthiourea; Thiourea, N-[3-(trifluoromethoxy)phenyl]-; 3-Trifluoromethoxyphenyl-thiourea; m-Trifluoromethoxyphenylthiourea; CAS 235101-42-5
EINECS	Contact for details

Quality Control

Our 3-Trifluoromethoxyphenylthiourea is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can accommodate custom purity requirements for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.