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L-Glycero-L-Galacto-Heptitol, 2,6-Anhydro-3,4-o-(1-Methylethylidene)-, 1,7-Bis(4-Methylbenzenesulfonate) CAS NO 228115-86-4


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CAS No.:228115-86-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

L-Glycero-L-Galacto-Heptitol, 2,6-Anhydro-3,4-o-(1-Methylethylidene)-, 1,7-Bis(4-Methylbenzenesulfonate) is a sophisticated, high-purity chemical intermediate characterized by its unique heptitol backbone protected with isopropylidene and tosylate groups. This compound matters as a critical chiral building block for the synthesis of complex carbohydrates, nucleosides, and other biologically active molecules, offering precise stereochemical control. It is primarily needed by research institutions and pharmaceutical companies engaged in advanced medicinal chemistry, carbohydrate chemistry, and the development of novel therapeutics and diagnostic agents.

Application

  • Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel nucleoside analogs and antiviral/anticancer drug candidates.
  • Carbohydrate Chemistry Research: Used as a protected heptitol derivative for constructing complex oligosaccharides, glycoconjugates, and glycomimetics.
  • Glycobiology Studies: Employed in the development of probes and inhibitors for studying carbohydrate-protein interactions and enzymatic pathways.
  • Chemical Biology Tool: Acts as a scaffold for creating labeled or modified sugars for metabolic labeling and imaging studies.
  • Process Development: Utilized in route scouting and scale-up processes for the production of high-value fine chemicals and APIs.

Basic Information

Product Name L-Glycero-L-Galacto-Heptitol, 2,6-Anhydro-3,4-o-(1-Methylethylidene)-, 1,7-Bis(4-Methylbenzenesulfonate)
CAS No. 228115-86-4
Molecular Formula C24H30O11S2
Molecular Weight 558.62 g/mol
Synonyms 1,7-Bis(4-methylbenzenesulfonyl)-2,6-anhydro-3,4-O-(1-methylethylidene)-L-glycero-L-galacto-heptitol; 2,6-Anhydro-3,4-O-isopropylidene-L-glycero-L-galacto-heptitol 1,7-bis(tosylate); Heptitol derivative tosylate; Protected heptitol ditosylate; L-Galacto-heptitol bis(tosylate) intermediate; Isopropylidene-protected heptitol ditosylate; Carbohydrate tosylate building block
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Quality Control

Our L-Glycero-L-Galacto-Heptitol derivative is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and KF for moisture content, to ensure it meets the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Chiral Purity ≥ 99.0% ee
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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