Description

2H-Pyran-4-Carboxaldehyde, Tetrahydro-3-Methyl-2-Oxo-, (3S,4R)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters as a versatile precursor for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to develop novel compounds with high enantiomeric purity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of novel, enantiomerically pure pesticides and herbicides.
• Asymmetric Catalysis: Serves as a precursor or ligand in the development of chiral catalysts for stereoselective reactions.
• Fine Chemical Production: Employed in the manufacture of complex fragrance and flavor ingredients requiring specific stereochemistry.
• Academic & R&D: A valuable tool for chemists in university and corporate labs exploring new synthetic methodologies and heterocyclic chemistry.
• Material Science Research: Investigated as a monomer or building block for novel chiral polymers and advanced materials.

Basic Information

Product Name	2H-Pyran-4-Carboxaldehyde, Tetrahydro-3-Methyl-2-Oxo-, (3S,4R)- (9Ci)
CAS No.	227805-00-7
Molecular Formula	C7H10O3
Molecular Weight	142.15 g/mol
Synonyms	(3S,4R)-3-Methyl-2-oxotetrahydro-2H-pyran-4-carboxaldehyde; (3S,4R)-3-Methyl-2-oxotetrahydropyran-4-carbaldehyde; Tetrahydro-3-methyl-2-oxo-2H-pyran-4-carboxaldehyde, (3S,4R)-; 4-Formyl-3-methyl-5,6-dihydro-2H-pyran-2-one; (3S,4R)-rel-3-Methyl-2-oxotetrahydro-2H-pyran-4-carboxaldehyde; Chiral Dihydropyranone aldehyde; 3-Methyl-2-oxotetrahydropyran-4-carboxaldehyde (enantiomer)
EINECS	Contact for details

Quality Control

Our 2H-Pyran-4-Carboxaldehyde, Tetrahydro-3-Methyl-2-Oxo-, (3S,4R)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high enantiomeric excess (ee) and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.