Description

1-Benzofuran-6-Yl Trifluoromethanesulfonate is a high-value triflate ester derivative of benzofuran, serving as a critical synthetic intermediate in advanced organic chemistry. Its primary commercial value lies in its excellent leaving group properties, enabling efficient cross-coupling reactions and functional group transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for constructing complex heterocyclic scaffolds and developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those containing benzofuran or related heterocyclic cores with potential biological activity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require the benzofuran pharmacophore.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Cross-Coupling Reactions: An effective electrophile in palladium-catalyzed reactions like Suzuki, Stille, and Negishi couplings to form carbon-carbon bonds.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating complex molecular libraries.
• Ligand and Catalyst Development: Used to synthesize sophisticated ligands for catalysis or as a precursor for metal-organic frameworks (MOFs).

Basic Information

Item	Details
Product Name	1-Benzofuran-6-Yl Trifluoromethanesulfonate
CAS No.	227752-25-2
Molecular Formula	C10H5F3O4S
Molecular Weight	278.21 g/mol
Synonyms	6-Benzofuranyl Triflate; 1-Benzofuran-6-ol Triflate; 6-(Trifluoromethanesulfonyloxy)benzofuran; Benzofuran-6-yl Triflate; 6-Hydroxybenzofuran Trifluoromethanesulfonate; 227752-25-2; 6-Triflyloxybenzofuran
EINECS	Contact for details

Quality Control

Every batch of 1-Benzofuran-6-Yl Trifluoromethanesulfonate is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic processes. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available with each shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.