Description

4,5-Pyridazinediol,Hexahydro-3-(Hydroxymethyl)-,(3R,4R,5R)-(9Ci) is a high-purity, stereochemically defined heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its multifunctional structure, which serves as a versatile chiral scaffold for constructing complex molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, process development, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in areas requiring stereochemical control.
• Medicinal Chemistry Research: Used as a constrained scaffold or building block in drug discovery programs to explore novel chemical space and structure-activity relationships (SAR).
• Agrochemical Synthesis: Serves as a precursor in the development of new, stereoselective crop protection agents and herbicides.
• Asymmetric Synthesis Catalyst Ligand Precursor: Its chiral diol functionality makes it a potential precursor for ligands used in asymmetric catalysis.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals and complex organic molecules for various high-value industries.
• Academic & Institutional Research: Utilized in universities and research institutes for studies in synthetic methodology, heterocyclic chemistry, and stereochemistry.

Basic Information

Product Name	4,5-Pyridazinediol,Hexahydro-3-(Hydroxymethyl)-,(3R,4R,5R)-(9Ci)
CAS No.	226988-19-8
Molecular Formula	C7H14N2O3
Molecular Weight	174.20 g/mol
Synonyms	(3R,4R,5R)-Hexahydro-3-(hydroxymethyl)-4,5-pyridazinediol; (3R,4R,5R)-3-(Hydroxymethyl)hexahydro-4,5-pyridazinediol; 1,4,5,6-Tetrahydro-3-pyridazinecarboxylic acid, 4,5-dihydroxy-, (3R,4R,5R)-; (3R,4R,5R)-4,5-Dihydroxyhexahydro-3-pyridazinecarbinol; Hexahydro-3-(hydroxymethyl)-4,5-pyridazinediol, (3R,4R,5R)-; Chiral Hexahydro-4,5-pyridazinediol derivative; (3R,4R,5R)-HHP derivative
EINECS	Contact for details

Quality Control

Every batch of 4,5-Pyridazinediol,Hexahydro-3-(Hydroxymethyl)-,(3R,4R,5R)-(9Ci) is produced and tested under a strict quality management system. Our products undergo rigorous analytical testing, including chiral purity verification, to ensure compliance with exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.