Description

Cyclopentanone, 2-(Hydroxymethyl)-5-(1-Methylethyl)- (9Ci) is a functionalized cyclopentanone derivative, a versatile chiral building block in advanced organic synthesis. Its molecular structure, featuring both a ketone and a hydroxymethyl group on the cyclopentane ring, makes it a critical intermediate for constructing complex molecules with high stereochemical control. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs), natural product analogs, and specialty fragrances.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Fine Chemical Synthesis: Used in the multi-step synthesis of natural products, complex heterocycles, and other high-value specialty chemicals.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development of new asymmetric catalytic reactions.
• Fragrance and Flavor Chemistry: Acts as a precursor for musk-like odorants and other complex aroma molecules due to its functionalized cyclopentanone core.
• Material Science Monomer: Potential use as a monomer or cross-linking agent in the development of specialized polymers with unique thermal or mechanical properties.

Basic Information

Product Name	Cyclopentanone, 2-(Hydroxymethyl)-5-(1-Methylethyl)- (9Ci)
CAS No.	226947-22-4
Molecular Formula	C9H16O2
Molecular Weight	156.22 g/mol
Synonyms	2-(Hydroxymethyl)-5-isopropylcyclopentanone; 5-Isopropyl-2-(hydroxymethyl)cyclopentanone; 2-(Hydroxymethyl)-5-(1-methylethyl)cyclopentanone; (5-Isopropyl-2-oxocyclopentyl)methanol
EINECS	Contact for details

Quality Control

Our Cyclopentanone, 2-(Hydroxymethyl)-5-(1-Methylethyl)- (9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including chiral purity assessment via HPLC, to meet the stringent requirements of pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with every batch to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider the use of desiccants or an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.