Description

4-Cyanobutylzinc Bromide is a highly reactive organozinc reagent, specifically a functionalized alkylzinc halide, essential for advanced organic synthesis. Its core value lies in enabling efficient carbon-carbon bond formation, particularly in cross-coupling reactions, which is critical for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for synthesizing novel active ingredients and functional intermediates.

Application

4-Cyanobutylzinc Bromide serves as a versatile building block in modern synthetic chemistry. Key application scenarios include:

• Pharmaceutical Intermediate Synthesis: Used in Negishi and other transition-metal-catalyzed cross-couplings to introduce the 4-cyanobutyl moiety into complex drug candidates and bioactive molecules.
• Agrochemical Research: Employed for the construction of novel herbicide and pesticide scaffolds that require specific nitrile-functionalized alkyl chains.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing specialized ligands or metal-organic frameworks (MOFs) with tailored properties.
• Material Science: Utilized in the synthesis of functional polymers or organic electronic materials where the nitrile group imparts specific polarity or binding characteristics.
• Fine Chemical Production: Applied in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring precise carbon chain elongation.
• Academic Research: A valuable tool in methodological studies for developing new catalytic cycles and exploring the reactivity of organometallic species.

Basic Information

Item	Detail
Product Name	4-Cyanobutylzinc Bromide
CAS No.	226570-68-9
Molecular Formula	C5H8BrNZn
Molecular Weight	219.42 g/mol
Synonyms	4-Cyanobutylzinc bromide solution; Bromo(4-cyanobutyl)zinc; Zinc, bromo(4-cyanobutyl)-; (4-Cyanobutyl)zinc bromide; 4-Cyanobutyl zinc bromide; 226570-68-9; Bromo(4-cyanobutyl)zinc (1:1:1)
EINECS	Contact for details

Quality Control

Our production of 4-Cyanobutylzinc Bromide adheres to stringent quality protocols. The product undergoes rigorous analytical testing, including titration for active zinc content and spectroscopic methods for identity and purity verification, to ensure batch-to-batch consistency and compliance with high-purity reagent standards. A comprehensive Certificate of Analysis (COA) detailing concentration, solvent, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and moisture-sensitive nature, this reagent must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures between 2°C and 8°C. The container should be kept in a cool, dry, and well-ventilated area, away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (IR)	Conforms to structure
Concentration	0.5 M in Tetrahydrofuran (typical)
Assay (Titration)	≥ 95% (as 4-Cyanobutylzinc Bromide)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.