Description

Cyclohexanamine, 3-Methyl-5-(1-Methylethyl)-, (1R,3S,5R)-Rel- (9Ci) is a high-purity, stereochemically defined chiral amine building block of significant interest in advanced organic synthesis. Its value lies in its rigid cyclohexane backbone and specific isopropyl substitution pattern, which provides a unique three-dimensional structure for constructing complex molecules with precise stereochemistry. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, chiral catalysts, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used as a building block for creating advanced, stereoselective herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Chiral Ligand & Catalyst Development: Serves as a precursor for synthesizing sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Flavor & Fragrance Chemistry: Employed in the synthesis of complex terpenoid-based aroma chemicals and flavorants due to its minty/menthol-like structural motifs.
• Material Science Research: Investigated as a monomer or modifying agent for creating polymers with specific chiral or steric properties.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions.

Basic Information

Item	Detail
Product Name	Cyclohexanamine, 3-Methyl-5-(1-Methylethyl)-, (1R,3S,5R)-Rel- (9Ci)
CAS No.	226548-59-0
Molecular Formula	C10H21N
Molecular Weight	155.28 g/mol
Synonyms	rel-(1R,3S,5R)-3-Methyl-5-(propan-2-yl)cyclohexan-1-amine; 3-Methyl-5-isopropylcyclohexylamine (stereoisomer); (-)-Menthan-3-amine (related stereoisomer); Chiral Isopropylmethylcyclohexylamine; (1R,3S,5R)-3-Methyl-5-(1-methylethyl)cyclohexanamine; Bicyclic amine derivative; Stereoisomeric cyclohexaneamine; CAS 226548-59-0
EINECS	Contact for details

Quality Control

Our production of Cyclohexanamine, 3-Methyl-5-(1-Methylethyl)-, (1R,3S,5R)-Rel- (9Ci) adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, identity confirmation by IR and NMR spectroscopy, and quantification of key impurities. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring full traceability and compliance with your research or cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its amine functionality and potential light sensitivity, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.