Description

2H-1,2-Oxazine-4,5-Diol, Tetrahydro-6-(Hydroxymethyl)-, (4R,5R,6S)-Rel- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its complex oxazine-diol structure makes it a valuable precursor for the development of novel pharmaceuticals and bioactive compounds. This material is primarily sought after by research institutions and fine chemical manufacturers specializing in asymmetric synthesis, medicinal chemistry, and the production of complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for complex target molecules.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to introduce specific stereochemistry and functional groups.
• Asymmetric Synthesis: Serves as a building block for constructing enantiomerically pure compounds in catalytic and stoichiometric asymmetric reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and other high-value products requiring precise stereocontrol.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists exploring new methodologies and complex natural product synthesis.

Basic Information

Product Name	2H-1,2-Oxazine-4,5-Diol, Tetrahydro-6-(Hydroxymethyl)-, (4R,5R,6S)-Rel- (9Ci)
CAS No.	226081-48-7
Molecular Formula	C5H9NO4
Molecular Weight	147.13 g/mol
Synonyms	(4R,5R,6S)-Tetrahydro-6-(hydroxymethyl)-2H-1,2-oxazine-4,5-diol; rel-(4R,5R,6S)-Tetrahydro-6-(hydroxymethyl)-2H-1,2-oxazine-4,5-diol; 6-(Hydroxymethyl)tetrahydro-2H-1,2-oxazine-4,5-diol (stereoisomer); Chiral Oxazine Diol Derivative; (4R,5R,6S)-6-(Hydroxymethyl)tetrahydro-2H-1,2-oxazine-4,5-diol; CAS 226081-48-7
EINECS	Contact for details

Quality Control

Our 2H-1,2-Oxazine-4,5-Diol, Tetrahydro-6-(Hydroxymethyl)-, (4R,5R,6S)-Rel- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.