Description

2H-Pyran-2-One,Tetrahydro-4-Hydroxy-5-Methyl-6-(1-Methylethyl)-,(4S,5S,6R)-(9Ci) is a high-purity, stereochemically defined lactone compound valued for its role as a key chiral intermediate and building block in advanced organic synthesis. Its precise stereochemistry at the 4, 5, and 6 positions makes it a critical component for producing enantiomerically pure pharmaceuticals and fine chemicals. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce complex molecular architectures with high optical purity.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in classes requiring specific stereochemical configurations.
• Agrochemical Synthesis: Used in the research and production of advanced, stereoselective pesticides and herbicides.
• Flavor & Fragrance Ingredient: Acts as a precursor for the development of complex, natural-identical flavor molecules and aroma chemicals.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and natural product analogs.
• Asymmetric Catalysis Research: Utilized as a standard or substrate in developing and testing new chiral catalysts and synthetic methodologies.
• Fine Chemical Production: Integral to the multi-step synthesis of high-value specialty chemicals for electronics and performance materials.

Basic Information

Item	Details
Product Name	2H-Pyran-2-One,Tetrahydro-4-Hydroxy-5-Methyl-6-(1-Methylethyl)-,(4S,5S,6R)-(9Ci)
CAS No.	224580-59-0
Molecular Formula	C9H16O3
Molecular Weight	172.22 g/mol
Synonyms	(4S,5S,6R)-Tetrahydro-4-hydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-one; (4S,5S,6R)-4-Hydroxy-5-methyl-6-(propan-2-yl)tetrahydro-2H-pyran-2-one; 4-Hydroxy-5-methyl-6-(1-methylethyl)tetrahydro-2H-pyran-2-one (stereoisomer); Dihydro-5-methyl-6-(1-methylethyl)-4H-pyran-4-one derivative; Optically active tetrahydro-2H-pyran-2-one derivative; Chiral γ-lactone intermediate; Lactone building block CAS 224580-59-0
EINECS	Contact for details

Quality Control

We supply 2H-Pyran-2-One,Tetrahydro-4-Hydroxy-5-Methyl-6-(1-Methylethyl)-,(4S,5S,6R)-(9Ci) with a strong commitment to quality and batch-to-batch consistency. Our products undergo rigorous quality testing, including chiral purity analysis, to ensure compliance with stringent industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each batch to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.