Description

2H-Pyran-4-Carboxylicacid,4-Aminotetrahydro-2-Methyl-,(2R,4S)-Rel-(9Ci) is a high-purity, stereochemically defined chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key building block for the development of complex, biologically active molecules, particularly in the pharmaceutical sector. This compound is essential for research chemists and process development scientists working on novel therapeutics, agrochemicals, and specialty fine chemicals where precise stereochemistry is critical for efficacy and safety.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in areas requiring complex heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the synthesis of advanced crop protection agents and herbicides that require specific stereoisomers for optimal activity.
• Asymmetric Catalysis Research: Serves as a valuable ligand precursor or chiral pool material in the development of new catalytic systems for enantioselective synthesis.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, including flavors, fragrances, and advanced materials.
• Academic & Industrial R&D: A key reagent for methodological studies in organic chemistry, supporting innovation in synthetic route design.

Basic Information

Product Name	2H-Pyran-4-Carboxylicacid,4-Aminotetrahydro-2-Methyl-,(2R,4S)-Rel-(9Ci)
CAS No.	224560-54-7
Molecular Formula	C7H11NO3
Molecular Weight	157.17 g/mol
Synonyms	(2R,4S)-4-Amino-2-methyltetrahydro-2H-pyran-4-carboxylic acid; rel-(2R,4S)-4-Amino-2-methyltetrahydro-2H-pyran-4-carboxylic acid; 4-Amino-2-methyltetrahydro-2H-pyran-4-carboxylic acid (relative configuration); 2H-Pyran-4-carboxylic acid, 4-amino-2-methyltetrahydro-, (2R,4S)-rel-; 224560-54-7; 4-Aminotetrahydro-2-methyl-2H-pyran-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized and undergoes rigorous analytical testing, including chiral purity determination by HPLC. A comprehensive Certificate of Analysis (COA) detailing identity, assay, chiral purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.