Description

(-)-Epigallocatechin 3-(4''-o-Methyl)Gallate is a specific, methylated derivative of the prominent green tea catechin, epigallocatechin gallate (EGCG). This structural modification enhances its metabolic stability and bioavailability, making it a compound of significant interest for advanced research and development. It is primarily sought by the pharmaceutical, nutraceutical, and life science industries for its potential bioactivity and as a critical reference standard.

Application

• Pharmaceutical R&D: Used as a high-purity reference standard and active pharmaceutical ingredient (API) intermediate in the development of therapeutic agents.
• Nutraceutical Formulation: Incorporated into advanced dietary supplements targeting specific health and wellness benefits due to its enhanced stability profile.
• Biochemical Research: Serves as a key tool compound in metabolic studies, signal transduction pathway analysis, and antioxidant mechanism research.
• Cosmeceuticals: Applied in the formulation of high-end skincare products for its potential anti-aging and protective properties.
• Analytical Chemistry: Essential as a certified reference material (CRM) for the qualitative and quantitative analysis of tea polyphenols in various matrices.

Basic Information

Item	Detail
Product Name	(-)-Epigallocatechin 3-(4''-o-Methyl)Gallate
CAS No.	224434-07-5
Molecular Formula	C23H20O11
Molecular Weight	472.40 g/mol
Synonyms	4''-O-Methyl-(-)-epigallocatechin gallate; 4''-O-Methyl-EGCG; (-)-Epigallocatechin 3-(4-O-methyl)gallate; 3-O-Galloyl-(-)-epigallocatechin 4''-methyl ether; EGCG 4''-Me; EGCG4''Me; 4''-Methyl-epigallocatechin gallate
EINECS	Contact for details

Quality Control

Our (-)-Epigallocatechin 3-(4''-o-Methyl)Gallate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets exacting standards for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation. The product is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.