Description

(S)-1-(Benzylideneamino)-3-Chloropropan-2-Ol is a chiral organic intermediate of significant interest in advanced synthetic chemistry. This compound matters for its role as a key building block in the synthesis of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by research and development laboratories, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of β-blockers, adrenergic agents, and other receptor-targeting molecules.
• Agrochemical Synthesis: Used in the research and production of chiral pesticides and herbicides, where stereochemistry is critical for biological activity and environmental safety.
• Catalyst and Ligand Preparation: Serves as a precursor for the synthesis of novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic and Industrial Research: A valuable reagent for methodological studies in organic chemistry, including asymmetric C-N and C-O bond-forming reactions.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals where optical purity is a key specification.

Basic Information

Product Name	(S)-1-(Benzylideneamino)-3-Chloropropan-2-Ol
CAS No.	224323-52-8
Molecular Formula	C10H12ClNO
Molecular Weight	197.66 g/mol
Synonyms	(S)-1-(Benzylideneamino)-3-chloro-2-propanol; (S)-3-Chloro-1-(phenylmethyleneamino)-2-propanol; (S)-1-(Benzylideneamino)-3-chloropropan-2-ol; (S)-1-(Phenylmethylideneamino)-3-chloropropan-2-ol; (S)-N-(3-Chloro-2-hydroxypropylidene)benzenamine; (S)-3-Chloro-2-hydroxypropylideneaniline; (S)-1-(Benzylideneamino)-3-chloro-2-propanol
EINECS	Contact for details

Quality Control

Our (S)-1-(Benzylideneamino)-3-Chloropropan-2-Ol is produced under strict quality management protocols to ensure batch-to-batch consistency and high optical purity. We employ advanced analytical techniques, including chiral HPLC and NMR spectroscopy, to verify identity, enantiomeric excess (ee), and chemical purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.